Luca Valenti Selected Research

Non-alcoholic Fatty Liver Disease

3/2022	Is there an 'ideal' diet for patients with NAFLD?
2/2022	Distinctive features of hepatocellular carcinoma in non-alcoholic fatty liver disease.
1/2022	TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models.
1/2022	A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores.
1/2022	The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis.
1/2022	Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b.
1/2022	Protective association of Klotho rs495392 gene polymorphism against hepatic steatosis in non-alcoholic fatty liver disease patients.
1/2022	Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease.
12/2021	PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date.
12/2021	Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma.

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Luca Valenti Research Topics

Disease

97	Non-alcoholic Fatty Liver Disease 03/2022 - 02/2002
72	Fibrosis (Cirrhosis) 02/2022 - 05/2004
35	Fatty Liver 12/2021 - 02/2002
32	Liver Diseases (Liver Disease) 01/2022 - 12/2005
29	Insulin Resistance 01/2022 - 02/2002
27	Inflammation (Inflammations) 06/2021 - 10/2006
25	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 08/2007
25	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 05/2004
14	Hemochromatosis (Bronze Diabetes) 01/2020 - 06/2007
13	Obesity 01/2022 - 06/2007
13	Iron Overload 01/2020 - 08/2007
12	Chronic Hepatitis C 01/2022 - 03/2008
11	Infections 01/2022 - 07/2005
10	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2014 - 06/2007
9	COVID-19 05/2022 - 01/2020
8	Alcoholic Fatty Liver 01/2022 - 08/2012
8	Hyperferritinemia 01/2015 - 10/2006
6	Hypertension (High Blood Pressure) 03/2022 - 09/2008
6	Anemia 01/2017 - 08/2009
5	Neoplasms (Cancer) 01/2022 - 09/2010
5	Atherosclerosis 11/2020 - 03/2011
5	Siderosis 09/2014 - 10/2006
5	Chronic Hepatitis (Chronic Active Hepatitis) 08/2013 - 05/2004
4	Alcoholism (Alcohol Abuse) 02/2022 - 01/2008
4	Hepatitis 12/2017 - 08/2007
4	Type 2 Diabetes Mellitus (MODY) 01/2016 - 02/2012
4	beta-Thalassemia (Cooley's Anemia) 09/2014 - 08/2007
3	Liver Neoplasms (Liver Cancer) 01/2022 - 02/2018
3	Carcinogenesis 12/2021 - 02/2010
3	Dyslipidemias (Dyslipidemia) 01/2020 - 07/2014
3	Glucose Intolerance 01/2020 - 02/2002
3	Hepatitis C 01/2020 - 07/2005
3	Abdominal Obesity 01/2017 - 06/2011
3	Hyperglycemia 02/2015 - 05/2012
3	Iron Deficiencies 05/2014 - 02/2010
2	Sepsis (Septicemia) 05/2022 - 12/2012
2	Disease Progression 01/2021 - 01/2020

Drug/Important Bio-Agent (IBA)

39	IronIBA 01/2021 - 03/2003
25	LipidsIBA 02/2022 - 02/2010
18	Proteins (Proteins, Gene)FDA Link 12/2021 - 05/2008
18	Ferritins (Ferritin)IBA 11/2021 - 10/2006
17	Phospholipases (Phospholipase)IBA 01/2022 - 04/2010
17	EnzymesIBA 07/2021 - 09/2008
16	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2008
16	HepcidinsIBA 01/2020 - 08/2007
12	Alanine Transaminase (SGPT)IBA 01/2022 - 09/2008
10	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2011
10	Insulin (Novolin)FDA Link 01/2021 - 06/2007
9	Triglycerides (Triacylglycerol)IBA 01/2020 - 09/2008
8	Transaminases (Aminotransferases)IBA 02/2022 - 09/2008
8	AcyltransferasesIBA 01/2022 - 01/2016
7	CytokinesIBA 10/2020 - 02/2002
7	Messenger RNA (mRNA)IBA 02/2020 - 05/2008
7	Transferrin (beta 2 Transferrin)IBA 01/2020 - 08/2007
7	Hormones (Hormone)IBA 01/2017 - 01/2012
5	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 06/2012
5	Antiviral Agents (Antivirals)IBA 01/2022 - 03/2011
5	Antisense OligonucleotidesIBA 01/2022 - 11/2018
5	CholesterolIBA 11/2021 - 09/2015
5	Pharmaceutical PreparationsIBA 06/2021 - 01/2013
5	AdiponectinIBA 01/2021 - 08/2012
4	ApolipoproteinsIBA 01/2022 - 07/2010
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 09/2015
4	Transcription Factors (Transcription Factor)IBA 12/2021 - 05/2008
4	Methionine (L-Methionine)FDA Link 10/2019 - 04/2010
4	InterferonsIBA 10/2019 - 02/2012
4	Vitamin A (Retinol)FDA LinkGeneric 01/2019 - 08/2015
4	AntioxidantsIBA 01/2018 - 07/2005
4	Telomerase (Telomerase Reverse Transcriptase)IBA 08/2017 - 02/2013
4	VLDL LipoproteinsIBA 08/2016 - 09/2014
4	Ribavirin (Virazole)FDA LinkGeneric 01/2014 - 02/2012
3	Genetic Markers (Genetic Marker)IBA 02/2022 - 07/2016
3	AntibodiesIBA 11/2021 - 01/2020
3	Complement System Proteins (Complement)IBA 11/2021 - 01/2021
3	ElementsIBA 10/2021 - 01/2013
3	nasIBA 01/2021 - 07/2012
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 02/2012
3	ABO Blood-Group SystemIBA 01/2021 - 10/2020
3	AdipokinesIBA 11/2020 - 06/2013
3	adiponutrinIBA 08/2013 - 04/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2013 - 02/2002
3	LDL CholesterolIBA 01/2008 - 12/2005
2	Apolipoproteins E (ApoE)IBA 01/2022 - 01/2021
2	Long Noncoding RNAIBA 01/2022 - 01/2019
2	Vitamin D FDA LinkGeneric 01/2022 - 03/2016
2	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2021
2	micaIBA 03/2021 - 02/2016
2	Sucrose (Saccharose)IBA 01/2021 - 01/2019
2	LigandsIBA 01/2021 - 03/2016
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2021 - 02/2020
2	GlucokinaseIBA 12/2020 - 01/2020
2	LeptinIBA 11/2020 - 10/2017
2	ResistinIBA 11/2020 - 06/2013
2	Peptides (Polypeptides)IBA 10/2020 - 07/2014
2	c-Mer Tyrosine KinaseIBA 01/2020 - 03/2016

Therapy/Procedure

20	Therapeutics 12/2021 - 05/2004
6	Liver Transplantation 01/2022 - 05/2004
4	Precision Medicine 12/2021 - 01/2019
4	Renal Dialysis (Hemodialysis) 05/2014 - 01/2007
3	Drug Therapy (Chemotherapy) 01/2019 - 07/2017